莫斯坦小姐的父亲十年前神秘失踪，从六年前起，每年都会有神秘人寄给她一颗贵重的珍珠。在收到一封诡异的匿名信之后，莫斯坦小姐决心向福尔摩斯求助。她交给福尔摩斯一张从父亲的遗物中发现的令人费解的印度纸，上面绘有大量的建筑和四个奇怪的签名。为了揭开谜题，福尔摩斯和华生陪她共赴一个神秘的约会……这次约会跟她父亲的死以及那些硕大的珍珠有关系吗，)印度纸上的奇怪签名究竟是什么意思？华生医生能否和令他一见钟情的莫斯坦小姐共结
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Chapter 1 The Science of Deduction
Chapter 2 The Statement of the Case
Chapter 3 In Quest of a Solution
Chapter 4 The Story of the Bald-Headed Man
Chapter 5 The Tragedy of Pondicherry Lodge
Chapter 6 Sherlock Holmes Gives a Demonstration
Chapter 7 The Episode of the Barrel
Chapter 8 The Baker Street Irregulars
Chapter 9 A Break in the Chain
Chapter 10 The End of the Islander
Chapter 11 The Great Agra Treasure
Chapter 12 The Strange Story of Jonathan Small