本套《练习册》的设计在内容与主题上均与《全新版21世纪大学英语读写教程》相关联,起到读写课程的延伸、巩固和增强的作用,同时,也为学生参加全国大学英语四、六级考试奠定坚实基础。《练习册》共分4册,每册共8个单元。每单元均由5部分组成:**部分为听力,第二部分为词汇和结构,第三部分为阅读,第四部分为翻译,第五部分为写作。
听力部分综合传统的听力题型并新增了四、六级考试新题型,设置短对话、长对话、短文理解、短文听写填空以及新闻或讲座。
词汇和结构部分围绕教材课文设置词汇、词组及语法结构的多项选择题。
阅读部分,各分册难度逐渐增加。每分册包括2篇仔细阅读,设多项选择题各5题;另1、3、5、7单元为快速阅读,设多项选择题和正误判断题;2、4、6、8单元为长篇阅读,设信息匹配题。
翻译部分,各分册采取递进难度,第2分册为英语较长句子翻译与汉语较长句子翻译;翻译的英文句子或段落均来自相对应单元的Text A;而汉语句子或汉语段落均来自课外,1、2分册的汉语句子翻译包含一定的语法结构知识。
写作部分,同样遵守循序渐进的原则,第2分册根据每段的首句写出短文。

Unit 1 Bonds of Friendships
Part Ⅰ Listening
Part Ⅱ Vocabulary and Structure
Part Ⅲ Reading Comprehension
Part Ⅳ Translation
Part Ⅴ Writing

Unit 2 Road to Success
Part Ⅰ Listening
Part Ⅱ Vocabulary and Structure
Part Ⅲ Reading Comprehension
Part Ⅳ Translation
Part Ⅴ Writing

Unit 3 Being True to One's Self
Part Ⅰ Listening
Part Ⅱ Vocabulary and Structure
Part Ⅲ Reading Comprehension
Part Ⅳ Translation
Part Ⅴ Writing

Unit 4 Cultural Values
Part Ⅰ Listening
Part Ⅱ Vocabulary and Structure
Part Ⅲ Reading Comprehension
Part Ⅳ Translation
Part Ⅴ Writing

Unit 5 A Piece of Advice
Part Ⅰ Listening
Part Ⅱ Vocabulary and Structure
Part Ⅲ Reading Comprehension
Part Ⅳ Translation
Part Ⅴ Writing

Unit 6 Future World
Part Ⅰ Listening
Part Ⅱ Vocabulary and Structure
Part Ⅲ Reading Comprehension
Part Ⅳ Translation
Part Ⅴ Writing

Unit 7 Non-Human Earthlings
Part Ⅰ Listening
Part Ⅱ Vocabulary and Structure
Part Ⅲ Reading Comprehension
Part Ⅳ Translation
Part Ⅴ Writing

Unit 8 New Technology
Part Ⅰ Listening
Part Ⅱ Vocabulary and Structure
Part Ⅲ Reading Comprehension
Part Ⅳ Translation
Part Ⅴ Writing
Scripts
Keys